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> > Preparing for an Infusion

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Step 1: Getting Your Factor tab
Step 1: Getting Your Factor tab
Step 2: Preparing for an Infusion tab
Step 2: Preparing for an Infusion tab
Step 3: Performing an Infusion tab
Step 3: Performing an Infusion tab
Step 4: Getting Support tab
Step 4: Getting Support tab

We are sharing this information so you’ll know what to expect from the process of preparing a NovoSeven® RT dose. For full instructions, refer to the FDA-approved patient information and Instructions for Use.

Do not attempt an infusion unless you have been trained by your health care provider or hemophilia treatment center.

Preparing a dose.

First, you’ll need to reconstitute NovoSeven® RT, which comes in powder form. “Reconstitute” means mixing it with diluent to create a liquid. Mixing is easy with MixPro®, the prefilled syringe that comes with every package of NovoSeven® RT.

Once you have washed your hands, choose a quiet place where you can prepare your dose on a clean, level surface, and gather everything you'll need:

  • Alcohol swabs
  • NovoSeven® RT vial, in your doctor’s recommended dose
  • MixPro® prefilled syringe with diluent
  • Vial adapter
  • Plunger rod
Reconstitution of NovoSeven® RT (Coagulation Factor VIIa [Recombinant]) thumbnail

Reconstitution Video

Watch our video to see how to mix a dose with MixPro®.

Watch Video

With MixPro®, preparing a dose is as quick as attach, twist, and mix.

The prefilled syringe means no extra steps to fill a syringe with diluent.

Selected Important Safety Information

What is the most important information I should know about NovoSeven® RT?

NovoSeven® RT may cause serious side effects, including:

  • Serious blood clots that form in veins and arteries with the use of NovoSeven® RT have been reported
  • Your healthcare provider should discuss the risks and explain the signs and symptoms of blood clots to you. Some signs of a blood clot may include pain, swelling, warmth, redness, or a lump in your legs or arms, chest pain, shortness of breath, or sudden severe headache and/or loss of consciousness or function
  • Your healthcare provider should monitor you for blood clots during treatment with NovoSeven® RT

What is NovoSeven® RT?

NovoSeven® RT (coagulation Factor VIIa, recombinant) is an injectable medicine used for:

  • Treatment of bleeding and prevention of bleeding for surgeries and procedures in adults and children with hemophilia A or B with inhibitors, congenital Factor VII (FVII) deficiency, and Glanzmann’s thrombasthenia with a decreased or absent response to platelet transfusions
  • Treatment of bleeding and prevention of bleeding for surgeries and procedures in adults with acquired hemophilia

Important Safety Information

What is the most important information I should know about NovoSeven® RT?

NovoSeven® RT may cause serious side effects, including:

  • Serious blood clots that form in veins and arteries with the use of NovoSeven® RT have been reported
  • Your healthcare provider should discuss the risks and explain the signs and symptoms of blood clots to you. Some signs of a blood clot may include pain, swelling, warmth, redness, or a lump in your legs or arms, chest pain, shortness of breath, or sudden severe headache and/or loss of consciousness or function
  • Your healthcare provider should monitor you for blood clots during treatment with NovoSeven® RT
  • You should not use NovoSeven® RT if you have ever had allergic (hypersensitivity) reactions, including severe, whole body reactions (anaphylaxis) to NovoSeven® RT, any of its ingredients, or mice, hamsters, or cows. Signs of allergic reaction include shortness of breath, rash, itching (pruritus), redness of the skin (erythema), or fainting/dizziness

What should I tell my healthcare provider before using NovoSeven® RT?

  • Tell your healthcare provider if you have any of the following, as these may increase your risk of blood clots:
    • congenital hemophilia and are also receiving treatment with aPCCs (activated prothrombin complex concentrates)
    • are an older patient particularly with acquired hemophilia and receiving other agents to stop bleeding
    • history of heart or blood vessel diseases
  • Tell your healthcare provider and pharmacist about all the medicines you take, including all prescription and non-prescription medicines, such as over-the-counter medicines, supplements, or herbal remedies

What are the possible side effects of NovoSeven® RT?

  • The most common and serious side effects are blood clots
  • Tell your healthcare provider about any side effects that bother you or do not go away, and seek medical help right away if you have signs of a blood clot or allergic reaction

Please click here for Prescribing Information